In full disclosure, I thoroughly enjoyed the book and do not have specific examples of inaccuracies. However, it worth noting that my advising professor for my Master's thesis recommended that I NOT use 6 Frigates as a source. Apparently some of Toll's early work had some academic problems. Basically, go into the book with some caution.
As to the original question, I've really enjoyed the informed discussion throughout these forums. I've learned quite a bit. Though I would put forward that perhaps this discussion has been a little to focused on the technical nature of which ship can throw a similar weight of iron to the U.S.S. Constitution. Isn't 'the weather gauge' also a viable answer? The skilled commander of a 32-gun ship with a crack crew and the weather gauge should be able to beat the Constitution. If not, I'm going to be dissapointed.