I've reported it a few times via F11, but I'll put it here as well
Noticed total loss of keyboard control via ship occasionally, and once or twice I've lost my mouse control completely.
1st time I was sailing in the OW, and noticed the ship wasn't responding to any input, but I could still type in the chat box fine. I ended up force closing the game and it was fixed.
2nd time was in a battle, I lost the HUD and again keyboard control was lost. I pressed F11 to report it and that brought the HUD back, along with control.
3rd time was loss of the mouse from the screen completely, it was in the after action report from a battle, and I was trying desperately to click on my loot
I ended up having to force close the game as no amount of trying would bring the mouse back